Professor Lee specializes in the study of epigenetic regulation by long noncoding RNA. Using X-inactivation as a model, her lab has made several contributions towards understanding how RNA directs chromatin and gene expression changes. She received her A.B. in Biochemistry & Molecular Biology from Harvard University, where she worked on antisense regulation with Professor Nancy Kleckner. She obtained the M.D.-Ph.D. degrees from the University of Pennsylvania School of Medicine, where she studied X-linked diseases with Professor Robert Nussbaum. At the Whitehead Institute/MIT, her postdoctoral work with Professor Rudolf Jaenisch delineated the X-inactivation center. She was Chief Resident of Clinical Pathology at the M.G.H., received the Basil O'Connor Award and the Pew Scholar Award as a young investigator, and was recently named a Distinguished Graduate of the University of Pennsylvania School of Medicine. She is also the recipient of the 2010 Molecular Biology Award from the National Academy of Sciences, USA, and is a Fellow of the American Association for the Advancement of Science (AAAS). She currently serves on the Board of Directors for the Genetics Society of America.
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